학술논문

Serum metabolomic profiles in dogs with chronic enteropathy
Document Type
article
Source
Journal of Veterinary Internal Medicine, Vol 36, Iss 5, Pp 1752-1759 (2022)
Subject
amino acid
canine
glycoprotein acetyls
lipid
metabolomics
Veterinary medicine
SF600-1100
Language
English
ISSN
1939-1676
0891-6640
Abstract
Abstract Background Metabolic profiles differ between healthy humans and those with inflammatory bowel disease. Few studies have examined metabolic profiles in dogs with chronic enteropathy (CE). Hypothesis Serum metabolic profiles of dogs with CE are significantly different from those of healthy dogs. Animals Fifty‐five dogs with CE and 204 healthy controls. Methods A cross‐sectional study. The serum concentrations of 99 metabolites measured using a canine‐specific proton nuclear magnetic resonance spectroscopy platform were studied. A 2‐sample unpaired t‐test was used to compare the 2 study samples. The threshold for significance was set at P