학술논문
Expression of visfatin in gingival crevicular fluid and gingival tissues in different periodontal conditions: a cross-sectional study
Document Type
article
Author
Source
BMC Oral Health, Vol 24, Iss 1, Pp 1-9 (2024)
Subject
Language
English
ISSN
1472-6831
Abstract
Abstract Background Studies have shown that visfatin is an inflammatory factor closely related to periodontitis. We examined the levels of visfatin in gingival crevicular fluid (GCF) and gingival tissues under different periodontal conditions, in order to provide more theoretical basis for exploring the role of visfatin in the pathogenesis of periodontitis. Methods We enrolled 87 subjects, with 43 in the chronic periodontitis (CP) group, 21 in the chronic gingivitis (CG) group, and 23 in the periodontal health (PH) group. Periodontal indexes (PD, AL, PLI, and BI) were recorded. GCF samples were collected for visfatin quantification, and gingival tissues were assessed via immunohistochemical staining. Results Visfatin levels in GCF decreased sequentially from CP to CG and PH groups, with statistically significant differences (P