학술논문
Rapid decline of neutralizing antibodies against SARS-CoV-2 among infected healthcare workers
Document Type
article
Author
Stéphane Marot; Isabelle Malet; Valentin Leducq; Karen Zafilaza; Delphine Sterlin; Delphine Planas; Adélie Gothland; Aude Jary; Karim Dorgham; Timothée Bruel; the Sorbonne Université SARS-CoV-2 Neutralizing Antibodies Study Group; Sonia Burrel; David Boutolleau; Olivier Schwartz; Guy Gorochov; Vincent Calvez; Anne-Geneviève Marcelin
Source
Nature Communications, Vol 12, Iss 1, Pp 1-7 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
The humoral immune response to SARS-CoV-2 infection is not yet fully understood. Here, Marot et al. monitor the longitudinal profile and neutralizing activity of IgG, IgA, and IgM among 26 healthcare workers and provide evidence for a short-lasting humoral immune protection due to a decrease of neutralizing antibody titers within 3 months.