학술논문
The genetic architecture of age-related hearing impairment revealed by genome-wide association analysis
Document Type
article
Author
Erna V. Ivarsdottir; Hilma Holm; Stefania Benonisdottir; Thorhildur Olafsdottir; Gardar Sveinbjornsson; Gudmar Thorleifsson; Hannes P. Eggertsson; Gisli H. Halldorsson; Kristjan E. Hjorleifsson; Pall Melsted; Arnaldur Gylfason; Gudny A. Arnadottir; Asmundur Oddsson; Brynjar O. Jensson; Aslaug Jonasdottir; Adalbjorg Jonasdottir; Thorhildur Juliusdottir; Lilja Stefansdottir; Vinicius Tragante; Bjarni V. Halldorsson; Hannes Petersen; Gudmundur Thorgeirsson; Unnur Thorsteinsdottir; Patrick Sulem; Ingibjorg Hinriksdottir; Ingileif Jonsdottir; Daniel F. Gudbjartsson; Kari Stefansson
Source
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Subject
Language
English
ISSN
2399-3642
Abstract
Erna Ivarsdottir et al. report a genome-wide association meta-analysis for age-related hearing loss in the Icelandic and UK populations. They identify 21 novel variants, 13 of which are rare, and reveal a genetic correlation between age-related hearing loss and tinnitus.