학술논문
Potent but transient immunosuppression of T-cells is a general feature of CD71+ erythroid cells
Document Type
article
Author
Tomasz M. Grzywa; Anna Sosnowska; Zuzanna Rydzynska; Michal Lazniewski; Dariusz Plewczynski; Klaudia Klicka; Milena Malecka-Gieldowska; Anna Rodziewicz-Lurzynska; Olga Ciepiela; Magdalena Justyniarska; Paulina Pomper; Marcin M. Grzybowski; Roman Blaszczyk; Michal Wegrzynowicz; Agnieszka Tomaszewska; Grzegorz Basak; Jakub Golab; Dominika Nowis
Source
Communications Biology, Vol 4, Iss 1, Pp 1-19 (2021)
Subject
Language
English
ISSN
2399-3642
Abstract
Grzywa et al. show that early CD71+ erythroid cells expand in the spleen of anemic mice and in humans and suppress T-cell activation. These results provide insight into the role of CECs in the immune response regulation.