학술논문
Rare SLC13A1 variants associate with intervertebral disc disorder highlighting role of sulfate in disc pathology
Document Type
article
Author
Gyda Bjornsdottir; Lilja Stefansdottir; Gudmar Thorleifsson; Patrick Sulem; Kristjan Norland; Egil Ferkingstad; Asmundur Oddsson; Florian Zink; Sigrun H. Lund; Muhammad S. Nawaz; G. Bragi Walters; Astros Th. Skuladottir; Sigurjon A. Gudjonsson; Gudmundur Einarsson; Gisli H. Halldorsson; Valgerdur Bjarnadottir; Gardar Sveinbjornsson; Anna Helgadottir; Unnur Styrkarsdottir; Larus J. Gudmundsson; Ole B. Pedersen; Thomas Folkmann Hansen; Thomas Werge; Karina Banasik; Anders Troelsen; Soren T. Skou; Lise Wegner Thørner; Christian Erikstrup; Kaspar Rene Nielsen; Susan Mikkelsen; DBDS Genetic Consortium; GO Consortium; Ingileif Jonsdottir; Aron Bjornsson; Ingvar H. Olafsson; Elfar Ulfarsson; Josep Blondal; Arnor Vikingsson; Soren Brunak; Sisse R. Ostrowski; Henrik Ullum; Unnur Thorsteinsdottir; Hreinn Stefansson; Daniel F. Gudbjartsson; Thorgeir E. Thorgeirsson; Kari Stefansson
Source
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Little is known about the biology of back pain, a leading cause of disability. Here the authors report 30 new back pain loci, implicating genes involved in cartilage/bone biology, as well as neurological and inflammatory processes.