학술논문
Current Positioning against Severe Infections Due to Klebsiella pneumoniae in Hospitalized Adults
Document Type
article
Author
Pablo Vidal-Cortés; Ignacio Martin-Loeches; Alejandro Rodríguez; Germán Bou; Rafael Cantón; Emili Diaz; Carmen De la Fuente; Julián Torre-Cisneros; Francisco Xavier Nuvials; Miguel Salavert; Gerardo Aguilar; Mercedes Nieto; Paula Ramírez; Marcio Borges; Cruz Soriano; Ricard Ferrer; Emilio Maseda; Rafael Zaragoza
Source
Antibiotics, Vol 11, Iss 9, p 1160 (2022)
Subject
Language
English
ISSN
2079-6382
Abstract
Infections due to Klebsiella pneumoniae have been increasing in intensive care units (ICUs) in the last decade. Such infections pose a serious problem, especially when antimicrobial resistance is present. We created a task force of experts, including specialists in intensive care medicine, anaesthesia, microbiology and infectious diseases, selected on the basis of their varied experience in the field of nosocomial infections, who conducted a comprehensive review of the recently published literature on the management of carbapenemase-producing Enterobacterales (CPE) infections in the intensive care setting from 2012 to 2022 to summarize the best available treatment. The group established priorities regarding management, based on both the risk of developing infections caused by K. pneumoniae and the risk of poor outcome. Moreover, we reviewed and updated the most important clinical entities and the new antibiotic treatments recently developed. After analysis of the priorities outlined, this group of experts established a series of recommendations and designed a management algorithm.