학술논문
Two high-risk susceptibility loci at 6p25.3 and 14q32.13 for Waldenström macroglobulinemia
Document Type
article
Author
Mary L. McMaster; Sonja I. Berndt; Jianqing Zhang; Susan L. Slager; Shengchao Alfred Li; Claire M. Vajdic; Karin E. Smedby; Huihuang Yan; Brenda M. Birmann; Elizabeth E. Brown; Alex Smith; Geffen Kleinstern; Mervin M. Fansler; Christine Mayr; Bin Zhu; Charles C. Chung; Ju-Hyun Park; Laurie Burdette; Belynda D. Hicks; Amy Hutchinson; Lauren R. Teras; Hans-Olov Adami; Paige M. Bracci; James McKay; Alain Monnereau; Brian K. Link; Roel C. H. Vermeulen; Stephen M. Ansell; Ann Maria; W. Ryan Diver; Mads Melbye; Akinyemi I. Ojesina; Peter Kraft; Paolo Boffetta; Jacqueline Clavel; Edward Giovannucci; Caroline M. Besson; Federico Canzian; Ruth C. Travis; Paolo Vineis; Elisabete Weiderpass; Rebecca Montalvan; Zhaoming Wang; Meredith Yeager; Nikolaus Becker; Yolanda Benavente; Paul Brennan; Lenka Foretova; Marc Maynadie; Alexandra Nieters; Silvia de Sanjose; Anthony Staines; Lucia Conde; Jacques Riby; Bengt Glimelius; Henrik Hjalgrim; Nisha Pradhan; Andrew L. Feldman; Anne J. Novak; Charles Lawrence; Bryan A. Bassig; Qing Lan; Tongzhang Zheng; Kari E. North; Lesley F. Tinker; Wendy Cozen; Richard K. Severson; Jonathan N. Hofmann; Yawei Zhang; Rebecca D. Jackson; Lindsay M. Morton; Mark P. Purdue; Nilanjan Chatterjee; Kenneth Offit; James R. Cerhan; Stephen J. Chanock; Nathaniel Rothman; Joseph Vijai; Lynn R. Goldin; Christine F. Skibola; Neil E. Caporaso
Source
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
Waldenström macroglobulinemia (WM)/lymphoplasmacytic lymphoma (LPL) is a non-Hodgkin-type B cell lymphoma. Here, the authors identify two risk loci for WM/LPL in a two-stage GWAS involving a family-oversampling approach and provide evidence for a functional role of the non-coding SNP rs116446171.