학술논문
Predictive factors for dissection-free sentinel node micrometastases in early oral squamous cell carcinoma
Document Type
article
Author
Takashi Matsuzuka; Kiyoaki Tsukahara; Seiichi Yoshimoto; Kazuaki Chikamatsu; Akihiro Shiotani; Isao Oze; Yoshiko Murakami; Takeshi Shinozaki; Yuichiro Enoki; Shinichi Ohba; Daisuke Kawakita; Nobuhiro Hanai; Yusuke Koide; Michi Sawabe; Yusuke Nakata; Yujiro Fukuda; Daisuke Nishikawa; Gaku Takano; Takahiro Kimura; Keisuke Oguri; Hitoshi Hirakawa; Yasuhisa Hasegawa
Source
Scientific Reports, Vol 13, Iss 1, Pp 1-5 (2023)
Subject
Language
English
ISSN
2045-2322
Abstract
Abstract This sentinel node (SN) biopsy trial aimed to assess its effectiveness in identifying predictive factors of micrometastases and to determine whether elective neck dissection is necessary in oral squamous cell carcinoma. This retrospective study included 55 patients from three previous trials, with positive SNs. The relationship between the sizes of the metastatic focus and metastasis in non-sentinel node (NSN) was investigated. Four of the 55 largest metastatic focus were isolated tumor cells, and the remaining 51 were ranged from 0.2 to 15 mm, with a median of 2.6 mm. The difference of prevalence between 46 negative- and 9 positive-NSN was statistically significant with regard to age, long diameter of primary site and number of cases with regional recurrence. In comparing the size of largest metastatic focus dividing the number of positive SN, with metastaic focus range of