학술논문

Life-threatening complications of streptococcal sepsis: a PICU contemporary series
Document Type
article
Source
Journal of Anesthesia, Analgesia and Critical Care, Vol 1, Iss 1, Pp 1-7 (2021)
Subject
Streptococcal sepsis complications
Intensive care
Mechanical ventilation
Septic shock
Tissue tropism phenotypes
Anesthesiology
RD78.3-87.3
Medical emergencies. Critical care. Intensive care. First aid
RC86-88.9
Language
English
ISSN
2731-3786
Abstract
Abstract Background Life-threatening streptococcal sepsis nowadays represents an uncommon event in previously healthy infants and children. Critically ill patients suffering from severe streptococcal sepsis complications may present with pre-antibiotic era clinical pictures and require a timely clinical approach to achieve restitutio ad integrum. Results We report a series of four patient groups affected by an uncommon life-threatening streptococcal sepsis, each of them exhibiting some distinct features. Streptococcus Agalactiae sepsis was associated with cerebral thrombotic/ischaemic lesions, whereas severe cardiogenic shock was prominent in the Streptococcus Viridans group; Streptococcus Faecalis and β-hemolytic group A Streptococcus patients mostly reported lung complications. Conclusions Previous antibiotic treatments should not delay aggressive treatment in the intensive care setting. Early diagnostic suspicion, as well as appropriate and aggressive treatment provided within an intensive care setting are crucial for the clinical outcome.