학술논문
Molecular and phenotypic profiling of colorectal cancer patients in West Africa reveals biological insights
Document Type
article
Author
Olusegun Isaac Alatise; Gregory C. Knapp; Avinash Sharma; Walid K. Chatila; Olukayode A. Arowolo; Olalekan Olasehinde; Olusola C. Famurewa; Adeleye D. Omisore; Akinwumi O. Komolafe; Olaejinrinde O. Olaofe; Aba I. Katung; David E. Ibikunle; Adedeji A. Egberongbe; Samuel A. Olatoke; Sulaiman O. Agodirin; Olusola A. Adesiyun; Ademola Adeyeye; Oladapo A. Kolawole; Akinwumi O. Olakanmi; Kanika Arora; Jeremy Constable; Ronak Shah; Azfar Basunia; Brooke Sylvester; Chao Wu; Martin R. Weiser; Ken Seier; Mithat Gonen; Zsofia K. Stadler; Yelena Kemel; Efsevia Vakiani; Michael F. Berger; Timothy A. Chan; David B. Solit; Jinru Shia; Francisco Sanchez-Vega; Nikolaus Schultz; Murray Brennan; J. Joshua Smith; T. Peter Kingham
Source
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
Understanding the molecular and phenotypic profile of colorectal cancer (CRC) in West Africa is important for early detection and treatment. Here, the authors use a multigene next-generation sequencing panel to identify genomic differences in Nigerian CRCs compared to those from TCGA and MSKCC cohorts.