학술논문
Intact fibroblast growth factor 23 in heart failure with reduced and mildly reduced ejection fraction
Document Type
article
Author
Source
BMC Cardiovascular Disorders, Vol 23, Iss 1, Pp 1-8 (2023)
Subject
Language
English
ISSN
1471-2261
Abstract
Abstract Background Fibroblast growth factor-23 (FGF23) has been associated to left ventricular (LV) hypertrophy and heart failure (HF) severity. We aimed to investigate the clinical correlates and prognostic value of intact FGF23 (iFGF23) in HF patients. Methods Patients with stable HF and left ventricular ejection fraction (LVEF) 50.9 pg/mL. LVEF decreased from the first iFGF23 tertile to the third tertile (p = 0.014). N-terminal pro-B-type natriuretic peptide (NT-proBNP) increased from the first to the third tertile (p = 0.001), while peak oxygen consumption decreased (p