학술논문

Anti-PD-1 Vasculitis of the central nervous system or radionecrosis?
Document Type
article
Source
Journal for ImmunoTherapy of Cancer, Vol 5, Iss 1, Pp 1-3 (2017)
Subject
Cerebral vasculitis
Immunotherapy
Radionecrosis
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Language
English
ISSN
2051-1426
Abstract
Abstract Commentary on « Cerebral vasculitis mimicking intracranial metastatic progression of lung cancer during PD-1 blockade » by Läubli H et al., J Immunother Cancer. 2017;5:46. The authors diagnosed a cerebral tumor-like lymphocytic vasculitis associated with anti-endothelial cell auto-antibodies secondary to anti-PD-1 therapy, treated by surgical resection and corticosteroids. We thought that this diagnosis should be discussed for at least two reasons. First, etiological explorations were not sufficient. Second, the diagnostic of radionecrosis should also be discussed.