학술논문
Management and outcomes in critically ill nonagenarian versus octogenarian patients
Document Type
article
Author
Raphael Romano Bruno; Bernhard Wernly; Malte Kelm; Ariane Boumendil; Alessandro Morandi; Finn H. Andersen; Antonio Artigas; Stefano Finazzi; Maurizio Cecconi; Steffen Christensen; Loredana Faraldi; Michael Lichtenauer; Johanna M. Muessig; Brian Marsh; Rui Moreno; Sandra Oeyen; Christina Agvald Öhman; Bernardo Bollen Pinto; Ivo W. Soliman; Wojciech Szczeklik; Andreas Valentin; Ximena Watson; Susannah Leaver; Carole Boulanger; Sten Walther; Joerg C. Schefold; Michael Joannidis; Yuriy Nalapko; Muhammed Elhadi; Jesper Fjølner; Tilemachos Zafeiridis; Dylan W. De Lange; Bertrand Guidet; Hans Flaatten; Christian Jung; on behalf of the VIP2 study group
Source
BMC Geriatrics, Vol 21, Iss 1, Pp 1-14 (2021)
Subject
Language
English
ISSN
1471-2318
Abstract
Abstract Background Intensive care unit (ICU) patients age 90 years or older represent a growing subgroup and place a huge financial burden on health care resources despite the benefit being unclear. This leads to ethical problems. The present investigation assessed the differences in outcome between nonagenarian and octogenarian ICU patients. Methods We included 7900 acutely admitted older critically ill patients from two large, multinational studies. The primary outcome was 30-day-mortality, and the secondary outcome was ICU-mortality. Baseline characteristics consisted of frailty assessed by the Clinical Frailty Scale (CFS), ICU-management, and outcomes were compared between octogenarian (80–89.9 years) and nonagenarian (> 90 years) patients. We used multilevel logistic regression to evaluate differences between octogenarians and nonagenarians. Results The nonagenarians were 10% of the entire cohort. They experienced a higher percentage of frailty (58% vs 42%; p