학술논문

Neurosyphilis with normal pressure hydrocephalus and dementia paralytica: serial clinical, laboratory and radiological correlations in the 21st century
Document Type
article
Source
Neurology International, Vol 8, Iss 3 (2016)
Subject
Neurosyphilis
Neuroradiology
Normal Pressure Hydrocephalus
Syphilis
Medicine
Internal medicine
RC31-1245
Neurosciences. Biological psychiatry. Neuropsychiatry
RC321-571
Language
English
ISSN
2035-8385
2035-8377
94774811
Abstract
We report a case of a 46-year-old man presenting with a progressive cognitive decline, ataxic gait, urinary incontinence for 4 months and neuroimaging consistent with normal pressure hydrocephalus. The atypical presentation of a progressively worsening dysphasia and a right hemiparesis dismissed as a vascular event 1 month earlier associated with normal pressure hydrocephalus prompted further investigations confirming neurosyphilis also manifesting as dementia paralytica. Treatment using consensus guidelines led to resumption of activities of daily living. Neurosyphilis, considered rare in the neuroimaging era, must still be considered a reversible cause of dementia and other neurological manifestations in contemporary neurological practice.