학술논문
Fatigue in patients with chronic disease: results from the population-based Lifelines Cohort Study
Document Type
article
Author
Yvonne M. J. Goërtz; Annemarie M. J. Braamse; Martijn A. Spruit; Daisy J. A. Janssen; Zjala Ebadi; Maarten Van Herck; Chris Burtin; Jeannette B. Peters; Mirjam A. G. Sprangers; Femke Lamers; Jos W. R. Twisk; Melissa S. Y. Thong; Jan H. Vercoulen; Suzanne E. Geerlings; Anouk W. Vaes; Rosanne J. H. C. G. Beijers; Martijn van Beers; Annemie M. W. J. Schols; Judith G. M. Rosmalen; Hans Knoop
Source
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Subject
Language
English
ISSN
2045-2322
50714090
50714090
Abstract
Abstract (1) To evaluate the prevalence of severe and chronic fatigue in subjects with and without chronic disease; (2) to assess to which extent multi-morbidity contributes to severe and chronic fatigue; and (3) to identify predisposing and associated factors for severe and chronic fatigue and whether these are disease-specific, trans-diagnostic, or generic. The Dutch Lifelines cohort was used, including 78,363 subjects with (n = 31,039, 53 ± 12 years, 33% male) and without (n = 47,324, 48 ± 12 years, 46% male) ≥ 1 of 23 chronic diseases. Fatigue was assessed with the Checklist Individual Strength-Fatigue. Compared to participants without a chronic disease, a higher proportion of participants with ≥ 1 chronic disease were severely (23% versus 15%, p