학술논문

A person-to-person transmission cluster of severe fever with thrombocytopenia syndrome characterized by mixed viral infections with familial and nosocomial clustering
Document Type
article
Source
Heliyon, Vol 10, Iss 2, Pp e24502- (2024)
Subject
Severe fever with thrombocytopenia syndrome virus
Person-to-person transmission
Genomic characterization
Familial clustering
Nosocomial infection
Science (General)
Q1-390
Social sciences (General)
H1-99
Language
English
ISSN
2405-8440
Abstract
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease with sporadic occurrence and high mortality. Herein, we report an example of the in-hospital transmission of SFTS virus (SFTSV) infections with familial and nosocomial clustering in Zhejiang Province, eastern China, from March to April 2023. The epidemiological investigation and genomic analysis revealed that at least eight suspected cases of SFTS occurred in this cluster, including one death and one asymptomatic case. Our report reemphasizes the risk of familial and nosocomial SFTSV infections in healthcare settings and the urgent need for the long-term systematic surveillance of SFTSV evolution in humans and animals in the eastern coastal regions of China.