학술논문

In-utero ultrasonography detection of fetal retinoblastoma and neonatal selective ophthalmic artery chemotherapy
Document Type
article
Source
Indian Journal of Ophthalmology, Vol 67, Iss 6, Pp 958-960 (2019)
Subject
Fetal retinoblastoma
intra-arterial chemotherapy neonatal retinoblastoma
pre-natal ultrasonography
retinoblastoma
Ophthalmology
RE1-994
Language
English
ISSN
0301-4738
1998-3689
Abstract
We report a case of non-familial, sporadic fetal retinoblastoma (RB) that was accidently detected at 39 weeks of gestation on pre-natal ultrasonography in left eye (OS). Post-natal examination revealed Group A and, Group D RB in right eye (OD) and OS, respectively. At 35 days, selective ophthalmic artery intra-arterial chemotherapy (IAC) was performed in OS and laser for OD. Pre-natal ultrasound and its application in RB are limited to those cases with a strong genetic predisposition. Our case was accidently detected at late gestation with no familial or genetic predisposition. In addition, this was the youngest reported case that received IAC on literature review.