학술논문
Features of Mpox infection: The analysis of the data submitted to the ID-IRI network
Document Type
article
Author
Gulden Eser-Karlidag; Enrique Chacon-Cruz; Yasemin Cag; Jose Arturo Martinez-Orozco; Humberto Gudino-Solorio; Raul Adrian Cruz-Flores; Andrea Gonzalez-Rodriguez; Daniela Martinez-Nieves; Mario Gomez-Zepeda; Andrea Calderon-Suarez; Hülya Çaşkurlu; Antonio Cascio; Ricardo Fernandez; Greisha M. Gonzales; Pedro Palma; Corneliu Petru Popescu; Roman Stebel; Botond Lakatos; Eva Nagy; Massimiliano Lanzafame; Amani El-Kholy; Buse Tuncer; Iva Christova; Stefka Krumova; Alexandre Naime Barbosa; Juan Pablo Escalera-Antezana; Ruben Castillo-Quino; Carlos Eduardo Gonzales-Flores; Miriam Moreira-Flores; Marcelo Felipe Batallanos-Huarachi; Christian Gomez-Davila; Rusmir Baljic; Tarsila Vieceli; Olumuyiwa Elijah Ariyo; Mireia Cairo Llobell; Osasona Oluwadamilola Gideon; Augustus Osborne; Umran Elbahr; Philippe Bossi; Antonella Tammaro; Alfonso J. Rodriguez-Morales; Hakan Erdem
Source
New Microbes and New Infections, Vol 53, Iss , Pp 101154- (2023)
Subject
Language
English
ISSN
2052-2975
Abstract
Background: Mpox is a rare zoonotic disease caused by the Mpox virus. On May 21, 2022, WHO announced the emergence of confirmed Mpox cases in countries outside the endemic areas in Central and West Africa. Methods: This multicentre study was performed through the Infectious Diseases International Research Initiative network. Nineteen collaborating centres in 16 countries participated in the study. Consecutive cases with positive Mpoxv-DNA results by the polymerase chain reaction test were included in the study. Results: The mean age of 647 patients included in the study was 34.5.98.6% of cases were males, 95.3% were homosexual-bisexual, and 92.2% had a history of sexual contact. History of smallpox vaccination was present in 3.4% of cases. The median incubation period was 7.0 days. The most common symptoms and signs were rashes in 99.5%, lymphadenopathy in 65.1%, and fever in 54.9%. HIV infection was present in 93.8% of cases, and 17.8% were followed up in the hospital for further treatment. In the two weeks before the rash, prodromal symptoms occurred in 52.8% of cases. The incubation period was 3.5 days shorter in HIV-infected Mpox cases with CD4 count