학술논문
Preoperative hemoglobin thresholds for survival equity in women and men
Document Type
article
Author
Florian Rumpf; Lotta Hof; Oliver Old; Patrick Friederich; Jens Friedrich; Josef Thoma; Maria Wittmann; Kai Zacharowski; Suma Choorapoikayil; Patrick Meybohm; German Patient Blood Management Network Collaborators; Olaf Baumhove; Samuel de Leeuw van Weenen; Markus Velten; Claudia Neumann; Andrea Kirfel; Nadine Straßberger-Nerschbach; Heidi Ehrentraut; Daniel Grigutsch; Vera Guttenthaler; Alma Puskarevic; Ghaith Mohssen; Jan Görtzen; Diana Narita; Lighvani Barbara; Michael Josef Huber; Valeska Lea Blum; Sabine Isik; Vanessa Neef; Florian Piekarski; Thomas Walther; Harald Keller; Andreas Schnitzbauer; Thomas Schmitz-Rixen; Kyriakos Oikonomou; Bjoern Steffen; Stefan Zeuzem; Marcus Czabanka; Felix Chun; Ingo Marzi; Timo Stöver; Shahram Ghanaati; Frank Louwen; M. Markus Mueller; Christoph Geisen; Erhard Seyfried; Eva Herrmann; Alexandra Bayer; Henry Weigt; Björn Lange; Ansgar Raadts; Christoph Haas; Johannes Duemmler; Ulf Lorenzen; Matthias Pagel; Thomas Puehler; Julius Pochhammer; Tim Klueter; Hajrullah Ahmeti; Dirk Bauerschlag; Henning Wieker; René Rusch; Gerd Molter; München Klinik; Janina Dana Jenke; Kira Kieserling; Dennie Scholle; U. Andrea Steinbicker; Alexander Zarbock; Sven Martens; Andres Schrader; G. R. Geissler; H. Hillmann; Georg Lenz; Klaus Schwendner; Viola Weber; Philipp Helmer; Sebastian Hottenrott; Peter Kranke; Daniel Roeder; Tobias Schlesinger; Magdalena Sitter; Jan Stumpner
Source
Frontiers in Medicine, Vol 11 (2024)
Subject
Language
English
ISSN
2296-858X
Abstract
Anemia affects humans throughout life, and is linked to higher morbidity and mortality. Unclear is whether hemoglobin values are equivalent between women and men. This study evaluates the association of preoperative hemoglobin levels with in-hospital mortality and estimates thresholds for survival equity between men and women. All adult patients undergoing surgery between 2010 and 2019 from 14 German hospitals were included in the study. Thresholds for survival equity were determined with generalized additive models. In total, 842,130 patients with a median in-hospital follow-up time of 7 days were analyzed. During follow-up 20,370 deaths occurred. Preoperative hemoglobin stratified in-hospital mortality (log-rank test p