학술논문
Organizing and running bioinformatics hackathons within Africa: The H3ABioNet cloud computing experience [version 2; peer review: 2 approved, 1 approved with reservations]
Document Type
article
Author
Azza E. Ahmed; Phelelani T. Mpangase; Sumir Panji; Shakuntala Baichoo; Yassine Souilmi; Faisal M. Fadlelmola; Mustafa Alghali; Shaun Aron; Hocine Bendou; Eugene De Beste; Mamana Mbiyavanga; Oussema Souiai; Long Yi; Jennie Zermeno; Don Armstrong; Brian D. O'Connor; Liudmila Sergeevna Mainzer; Michael R. Crusoe; Ayton Meintjes; Peter Van Heusden; Gerrit Botha; Fourie Joubert; C. Victor Jongeneel; Scott Hazelhurst; Nicola Mulder
Source
AAS Open Research, Vol 1 (2019)
Subject
Language
English
ISSN
2515-9321
Abstract
The need for portable and reproducible genomics analysis pipelines is growing globally as well as in Africa, especially with the growth of collaborative projects like the Human Health and Heredity in Africa Consortium (H3Africa). The Pan-African H3Africa Bioinformatics Network (H3ABioNet) recognized the need for portable, reproducible pipelines adapted to heterogeneous computing environments, and for the nurturing of technical expertise in workflow languages and containerization technologies. Building on the network’s Standard Operating Procedures (SOPs) for common genomic analyses, H3ABioNet arranged its first Cloud Computing and Reproducible Workflows Hackathon in 2016, with the purpose of translating those SOPs into analysis pipelines able to run on heterogeneous computing environments and meeting the needs of H3Africa research projects. This paper describes the preparations for this hackathon and reflects upon the lessons learned about its impact on building the technical and scientific expertise of African researchers. The workflows developed were made publicly available in GitHub repositories and deposited as container images on Quay.io.