학술논문
Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair
Document Type
article
Author
Source
Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
Subject
Language
English
ISSN
2041-1723
54673887
54673887
Abstract
Post-translational modifications are critical for regulating the DNA damage response. Here, the authors identify a methylation-deubiquitination crosstalk between methyltransferase PRMT1 and deubiquitinase USP11, showing that the enzymes regulate each other’s functions in DNA repair.