학술논문
COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
Document Type
article
Author
Source
Communications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
Subject
Language
English
ISSN
2399-3642
Abstract
Amila Suraweera et al. use a range of biochemical and in vitro cellular assays to examine the role of the COMMD4 in DNA repair. Their results suggest that COMMD4 interacts with the histone H2A-H2B during repair of double-stranded DNA breaks, thereby maintaining genomic stability by regulating chromatin structure.