학술논문
Coupled protein synthesis and ribosome-guided piRNA processing on mRNAs
Document Type
article
Author
Source
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
Ribosome can mediate piRNA biogenesis from long non-coding RNAs following translation of the short open reading frames. Here the authors show that 80S ribosome also guides piRNA production from 3’ UTR of protein-coding genes after translation of long open reading frames, indicating a general piRNA biogenesis mechanism regardless of their precursor ORF length.