학술논문

Symptomatic Female Genital Tract Infections Due to Neisseria meningitidis in Athens, Greece
Document Type
article
Source
Diagnostics, Vol 11, Iss 7, p 1265 (2021)
Subject
N. meningitidis
unusual presentations
female genital tract infections
serogroups
molecular typing
MLST
Medicine (General)
R5-920
Language
English
ISSN
11071265
2075-4418
Abstract
Neisseria meningitidis is considered as an obligate human pathogen and can cause life-threatening diseases like meningitis and/or septicaemia. Occasionally, it can be recovered from infections outside the bloodstream or central nervous system, like respiratory, ocular, joint, urogenital or other unusual sites. Herein, we present two rare cases of female genital infections due to N. meningitidis within a two-year period (2019–2020), identified as serogroup B (MenB) and Y (MenY), respectively. Genotypic analysis for PorA, FetA and MLST revealed the following characteristics: MenB: 7-12, 14, F5-36, 1572cc and MenY: 5-1,10-1, F4-5, 23cc, respectively. Such unusual presentations should alert the clinicians and microbiologists not to exclude N. meningitidis from routine diagnosis and the need of early detection. This is the first report in Greece, and, to our knowledge, in Europe since 2005 describing meningococcal female genital infections.