학술논문
Diet-induced disorders in rats are more efficiently attenuated by initial rather than delayed supplementation with polyphenol-rich berry fibres
Document Type
article
Source
Journal of Functional Foods, Vol 22, Iss , Pp 556-564 (2016)
Subject
Language
English
ISSN
1756-4646
Abstract
The effects of blackcurrant and strawberry fibre on high-fat diet-induced metabolic disorders in rats were compared. The blackcurrant and strawberry preparations were obtained from fruit pomace and contained 66.5 and 51.3% dietary fibre and 4.9 and 5.5% polyphenols, respectively. A high-fat diet was supplemented with the blackcurrant or strawberry fibre for the entire 8 weeks of experimental feeding or for 4 weeks, starting at week 5. Obesity, dyslipidaemia, hyperinsulinaemia and altered microbial metabolism in the distal intestine were noted in rats fed a high-fat diet. The 8-week supplementation with blackcurrant fibre decreased body weight, whereas both fibres decreased epididymal fat mass, increased the caecal concentration of short-chain fatty acids, prevented hyperinsulinaemia and decreased cholesterolaemia. Thus, pomace-derived blackcurrant and strawberry fibre attenuate disorders induced by a high-fat diet; however, initial dietary supplementation is more efficient than the same, but delayed, intervention.