학술논문

The effect of cardiovascular diseases on the course of multiple sclerosis (review of literature)
Document Type
article
Source
Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, Vol 26, Iss 3, Pp 31-42 (2020)
Subject
multiple sclerosis
comorbidity
vascular comorbidity
hypertension
stroke
chronic heart failure
ischemic heart disease
myocardial infarction
dyslipidemia
obesity
Medicine (General)
R5-920
Language
Russian
ISSN
1607-4181
Abstract
Comorbidity is one of the factors determining the course of multiple sclerosis. Cardiovascular pathology is one of the most common in the population as a whole, especially in age groups over 50. Several studies showed that arterial hypotension and dyslipidemia affected the course, progression rate, and neuroimaging characteristics of patients with multiple sclerosis. An important issue is the effect of disease modifying therapy on the course of concomitant diseases in patients with multiple sclerosis and the effect of concomitant diseases on the effectiveness and safety of disease modifying therapy. The question of the use of statins in multiple sclerosis remains controversial. This review presents data on vascular comorbidity in multiple sclerosis, including the prevalence of risk factors for cardiovascular pathology and concomitant vascular diseases in the population of patients with multiple sclerosis. Data on the effect of cardiovascular pathology on the course and treatment of multiple sclerosis were also analyzed.