학술논문
Microdiscectomy compared with transforaminal epidural steroid injection for persistent radicular pain caused by prolapsed intervertebral disc: the NERVES RCT
Document Type
article
Author
Martin J Wilby; Ashley Best; Eifiona Wood; Girvan Burnside; Emma Bedson; Hannah Short; Dianne Wheatley; Daniel Hill-McManus; Manohar Sharma; Simon Clark; Jennifer Bostock; Sally Hay; Ganesan Baranidharan; Cathy Price; Richard Mannion; Peter J Hutchinson; Dyfrig A Hughes; Anthony Marson; Paula R Williamson
Source
Health Technology Assessment, Vol 25, Iss 24 (2021)
Subject
Language
English
ISSN
1366-5278
2046-4924
2046-4924
Abstract
Background: Sciatica is a common condition reported to affect > 3% of the UK population at any time and is most often caused by a prolapsed intervertebral disc. Currently, there is no uniformly adopted treatment strategy. Invasive treatments, such as surgery (i.e. microdiscectomy) and transforaminal epidural steroid injection, are often reserved for failed conservative treatment. Objective: To compare the clinical effectiveness and cost-effectiveness of microdiscectomy with transforaminal epidural steroid injection for the management of radicular pain secondary to lumbar prolapsed intervertebral disc for non-emergency presentation of sciatica of