학술논문
Genetic loci associated with heart rate variability and their effects on cardiac disease risk
Document Type
article
Author
Ilja M. Nolte; M. Loretto Munoz; Vinicius Tragante; Azmeraw T. Amare; Rick Jansen; Ahmad Vaez; Benedikt von der Heyde; Christy L. Avery; Joshua C. Bis; Bram Dierckx; Jenny van Dongen; Stephanie M. Gogarten; Philippe Goyette; Jussi Hernesniemi; Ville Huikari; Shih-Jen Hwang; Deepali Jaju; Kathleen F. Kerr; Alexander Kluttig; Bouwe P. Krijthe; Jitender Kumar; Sander W. van der Laan; Leo-Pekka Lyytikäinen; Adam X. Maihofer; Arpi Minassian; Peter J. van der Most; Martina Müller-Nurasyid; Michel Nivard; Erika Salvi; James D. Stewart; Julian F. Thayer; Niek Verweij; Andrew Wong; Delilah Zabaneh; Mohammad H. Zafarmand; Abdel Abdellaoui; Sulayma Albarwani; Christine Albert; Alvaro Alonso; Foram Ashar; Juha Auvinen; Tomas Axelsson; Dewleen G. Baker; Paul I. W. de Bakker; Matteo Barcella; Riad Bayoumi; Rob J. Bieringa; Dorret Boomsma; Gabrielle Boucher; Annie R. Britton; Ingrid Christophersen; Andrea Dietrich; George B. Ehret; Patrick T. Ellinor; Markku Eskola; Janine F. Felix; John S. Floras; Oscar H. Franco; Peter Friberg; Maaike G. J. Gademan; Mark A. Geyer; Vilmantas Giedraitis; Catharina A. Hartman; Daiane Hemerich; Albert Hofman; Jouke-Jan Hottenga; Heikki Huikuri; Nina Hutri-Kähönen; Xavier Jouven; Juhani Junttila; Markus Juonala; Antti M. Kiviniemi; Jan A. Kors; Meena Kumari; Tatiana Kuznetsova; Cathy C. Laurie; Joop D. Lefrandt; Yong Li; Yun Li; Duanping Liao; Marian C. Limacher; Henry J. Lin; Cecilia M. Lindgren; Steven A. Lubitz; Anubha Mahajan; Barbara McKnight; Henriette Meyer zu Schwabedissen; Yuri Milaneschi; Nina Mononen; Andrew P. Morris; Mike A. Nalls; Gerjan Navis; Melanie Neijts; Kjell Nikus; Kari E. North; Daniel T. O'Connor; Johan Ormel; Siegfried Perz; Annette Peters; Bruce M. Psaty; Olli T. Raitakari; Victoria B. Risbrough; Moritz F. Sinner; David Siscovick; Johannes H. Smit; Nicholas L. Smith; Elsayed Z. Soliman; Nona Sotoodehnia; Jan A. Staessen; Phyllis K. Stein; Adrienne M. Stilp; Katarzyna Stolarz-Skrzypek; Konstantin Strauch; Johan Sundström; Cees A. Swenne; Ann-Christine Syvänen; Jean-Claude Tardif; Kent D. Taylor; Alexander Teumer; Timothy A. Thornton; Lesley E. Tinker; André G. Uitterlinden; Jessica van Setten; Andreas Voss; Melanie Waldenberger; Kirk C. Wilhelmsen; Gonneke Willemsen; Quenna Wong; Zhu-Ming Zhang; Alan B. Zonderman; Daniele Cusi; Michele K. Evans; Halina K. Greiser; Pim van der Harst; Mohammad Hassan; Erik Ingelsson; Marjo-Riitta Järvelin; Stefan Kääb; Mika Kähönen; Mika Kivimaki; Charles Kooperberg; Diana Kuh; Terho Lehtimäki; Lars Lind; Caroline M. Nievergelt; Chris J. O'Donnell; Albertine J. Oldehinkel; Brenda Penninx; Alexander P. Reiner; Harriëtte Riese; Arie M. van Roon; John D. Rioux; Jerome I. Rotter; Tamar Sofer; Bruno H. Stricker; Henning Tiemeier; Tanja G. M. Vrijkotte; Folkert W. Asselbergs; Bianca J. J. M. Brundel; Susan R. Heckbert; Eric A. Whitsel; Marcel den Hoed; Harold Snieder; Eco J. C. de Geus
Source
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Subject
Language
English
ISSN
2041-1723
Abstract
Heart rate variability (HRV) describes the individual variation in cardiac cycle duration and is a measure of vagal control of heart rate. Here, the authors identify seventeen single-nucleotide polymorphisms associated with HRV, lending new insight into the vagal regulation of heart rhythm.