학술논문

Left atrial volume changes during exercise stress echocardiography in heart failure and hypertrophic cardiomyopathy
Document Type
article
Source
Hellenic Journal of Cardiology, Vol 67, Iss , Pp 9-18 (2022)
Subject
E/e’ ratio
exercise stress echocardiography
left atrial volume index
left ventricular ejection fraction
mitral regurgitation
Diseases of the circulatory (Cardiovascular) system
RC666-701
Language
English
ISSN
1109-9666
Abstract
Objective: We aimed to assess feasibility and functional correlates of left atrial volume index (LAVI) changes during exercise stress echocardiography (ESE). Methods: ESE on a bike or treadmill was performed in 363 patients with heart failure with preserved ejection fraction (HFpEF, n = 173), reduced ejection fraction (HFrEF, n = 59), or hypertrophic cardiomyopathy (HCM, n = 131). The LAVI stress-rest increase ≥6.8 ml/m2 was defined as dilation. Results: LAVI measurements were feasible in 100%. LAVI did not change in HFrEF being at rest 32 (25-45) vs at stress 36 (24-54) ml/m2, P = NS and in HCM at rest 35 (26-48) vs at stress 38 (28-48) ml/m2, P = NS, whereas it decreased in HFpEF from 30 (24-40) to 29 (21-37) ml/m2 at stress, P = 0.007. LA dilation occurred in 107 (30%) patients (27% with treadmill vs 33% with bike ESE, P = NS): 26 with HFpEF (15%), 26 with HFrEF (44%), and 55 with HCM (42%) with P 14 at rest with odds ratio (OR) 4.4, LVEF