학술논문

Exploring the potential of microfluidics for next-generation drug delivery systems
Document Type
article
Source
OpenNano, Vol 12, Iss , Pp 100150- (2023)
Subject
Microfluidics
Drug delivery
Drug carrier
Microneedles
Precision
Robotics
Therapeutics. Pharmacology
RM1-950
Language
English
ISSN
2352-9520
Abstract
The platform of microfluidics offers a precise control and manipulation over fluids at a small scale and therefore has gained much attention in recent times. This topic is currently applied to automation and high-throughput analysis in several areas, including extraction of DNA, RNA and proteins, gene identification, gene assembly, cloning, single-cell analysis, organs grown on chips, PCR, drug screening, toxicity testing and drug delivery. Conventional methods used for drug delivery are sometimes non-targeted leading to loss of administered drugs and reduced drug effectiveness. Recent advances in microfluidics allow precise dose-dependent delivery of a drug to a targeted location. Several microfluidics designs have been implemented to improve the precision of treatment in clinics. This review highlights currently available tools in microfluidics, designs for drug carriers, delivery methods, robotics and artificial intelligence in the field of microfluidics.