학술논문
DNA methylation predicts age and provides insight into exceptional longevity of bats
Document Type
article
Author
Gerald S. Wilkinson; Danielle M. Adams; Amin Haghani; Ake T. Lu; Joseph Zoller; Charles E. Breeze; Bryan D. Arnold; Hope C. Ball; Gerald G. Carter; Lisa Noelle Cooper; Dina K. N. Dechmann; Paolo Devanna; Nicolas J. Fasel; Alexander V. Galazyuk; Linus Günther; Edward Hurme; Gareth Jones; Mirjam Knörnschild; Ella Z. Lattenkamp; Caesar Z. Li; Frieder Mayer; Josephine A. Reinhardt; Rodrigo A. Medellin; Martina Nagy; Brian Pope; Megan L. Power; Roger D. Ransome; Emma C. Teeling; Sonja C. Vernes; Daniel Zamora-Mejías; Joshua Zhang; Paul A. Faure; Lucas J. Greville; Steve Horvath
Source
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Subject
Language
English
ISSN
2041-1723
Abstract
DNA methylation profiles from 26 bat species accurately predicts chronological age, while longevity-related methylation patterns across the genome suggest that bat longevity results from augmented immune response and cancer suppression.