학술논문

Clinical features and risk factors for atazanavir (ATV)-associated urolithiasis: a case-control study.
Document Type
article
Source
PLoS ONE, Vol 9, Iss 11, p e112836 (2014)
Subject
Medicine
Science
Language
English
ISSN
1932-6203
Abstract
OBJECTIVES: Clinical features and risk factors for atazanavir (ATV)-associated urolithiasis have not been fully investigated. METHODS: We reviewed all cases of ATV-containing urolithiasis identified by infrared spectrophotometry among HIV-infected patients over a 5-year period to describe their clinical features and outcome. A case-control study was performed to identify risk factors associated with ATV-associated urolithiasis using univariate and multivariate logistic regression analyses. RESULTS: 30 cases of ATV-associated urolithiasis were analyzed. Patients were mostly men (87%), median age: 45.5 years, median CD4 cell count: 443 cells/µL and 97% had plasma HIV RNA level