학술논문
Interethnic analyses of blood pressure loci in populations of East Asian and European descent
Document Type
article
Author
Fumihiko Takeuchi; Masato Akiyama; Nana Matoba; Tomohiro Katsuya; Masahiro Nakatochi; Yasuharu Tabara; Akira Narita; Woei-Yuh Saw; Sanghoon Moon; Cassandra N. Spracklen; Jin-Fang Chai; Young-Jin Kim; Liang Zhang; Chaolong Wang; Huaixing Li; Honglan Li; Jer-Yuarn Wu; Rajkumar Dorajoo; Jovia L. Nierenberg; Ya Xing Wang; Jing He; Derrick A. Bennett; Atsushi Takahashi; Yukihide Momozawa; Makoto Hirata; Koichi Matsuda; Hiromi Rakugi; Eitaro Nakashima; Masato Isono; Matsuyuki Shirota; Atsushi Hozawa; Sahoko Ichihara; Tatsuaki Matsubara; Ken Yamamoto; Katsuhiko Kohara; Michiya Igase; Sohee Han; Penny Gordon-Larsen; Wei Huang; Nanette R. Lee; Linda S. Adair; Mi Yeong Hwang; Juyoung Lee; Miao Li Chee; Charumathi Sabanayagam; Wanting Zhao; Jianjun Liu; Dermot F. Reilly; Liang Sun; Shaofeng Huo; Todd L. Edwards; Jirong Long; Li-Ching Chang; Chien-Hsiun Chen; Jian-Min Yuan; Woon-Puay Koh; Yechiel Friedlander; Tanika N. Kelly; Wen Bin Wei; Liang Xu; Hui Cai; Yong-Bing Xiang; Kuang Lin; Robert Clarke; Robin G. Walters; Iona Y. Millwood; Liming Li; John C. Chambers; Jaspal S. Kooner; Paul Elliott; Pim van der Harst; The International Genomics of Blood Pressure (iGEN-BP) Consortium; Zhengming Chen; Makoto Sasaki; Xiao-Ou Shu; Jost B. Jonas; Jiang He; Chew-Kiat Heng; Yuan-Tsong Chen; Wei Zheng; Xu Lin; Yik-Ying Teo; E-Shyong Tai; Ching-Yu Cheng; Tien Yin Wong; Xueling Sim; Karen L. Mohlke; Masayuki Yamamoto; Bong-Jo Kim; Tetsuro Miki; Toru Nabika; Mitsuhiro Yokota; Yoichiro Kamatani; Michiaki Kubo; Norihiro Kato
Source
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
Blood pressure (BP) is a major risk factor for cardiovascular disease and more than 200 genetic loci associated with BP are known. Here, the authors perform discovery GWAS for BP in East Asians and meta-analysis in East Asians and Europeans and report ancestry-specific BP SNPs and selection signals.