학술논문
Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer
Document Type
article
Author
Smruthy Sivakumar; Dexter X. Jin; Hanna Tukachinsky; Karthikeyan Murugesan; Kimberly McGregor; Natalie Danziger; Dean Pavlick; Ole Gjoerup; Jeffrey S. Ross; Robert Harmon; Jon Chung; Brennan Decker; Lucas Dennis; Garrett M. Frampton; Luciana Molinero; Steffi Oesterreich; Jeffrey M. Venstrom; Geoffrey R. Oxnard; Priti S. Hegde; Ethan S. Sokol
Source
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Subject
Language
English
ISSN
2041-1723
Abstract
Liquid biopsies could be valuable tools to monitor breast cancer progression and evolution. Here, the authors investigate genomic profiling of tissue and liquid biopsies in a large cohort of patients with breast cancer during the course of therapy to characterise tumour evolution and acquired mutations.