학술논문

Artificial intelligence for precision medicine in autoimmune liver disease
Document Type
article
Source
Frontiers in Immunology, Vol 13 (2022)
Subject
machine learning
genomics
radiomics
digital pathology
autoimmunity
deep learning
Immunologic diseases. Allergy
RC581-607
Language
English
ISSN
1664-3224
Abstract
Autoimmune liver diseases (AiLDs) are rare autoimmune conditions of the liver and the biliary tree with unknown etiology and limited treatment options. AiLDs are inherently characterized by a high degree of complexity, which poses great challenges in understanding their etiopathogenesis, developing novel biomarkers and risk-stratification tools, and, eventually, generating new drugs. Artificial intelligence (AI) is considered one of the best candidates to support researchers and clinicians in making sense of biological complexity. In this review, we offer a primer on AI and machine learning for clinicians, and discuss recent available literature on its applications in medicine and more specifically how it can help to tackle major unmet needs in AiLDs.