학술논문

Multiple imputation of missing data in multilevel ecological momentary assessments: an example using smoking cessation study data
Document Type
article
Source
Frontiers in Digital Health, Vol 5 (2023)
Subject
multilevel data
multilevel multiple imputation
non-ignorable missing data
ecological momentary assessments
multilevel Bayesian vector autoregressive model
Medicine
Public aspects of medicine
RA1-1270
Electronic computers. Computer science
QA75.5-76.95
Language
English
ISSN
2673-253X
Abstract
Advances in digital technology have greatly increased the ease of collecting intensive longitudinal data (ILD) such as ecological momentary assessments (EMAs) in studies of behavior changes. Such data are typically multilevel (e.g., with repeated measures nested within individuals), and are inevitably characterized by some degrees of missingness. Previous studies have validated the utility of multiple imputation as a way to handle missing observations in ILD when the imputation model is properly specified to reflect time dependencies. In this study, we illustrate the importance of proper accommodation of multilevel ILD structures in performing multiple imputations, and compare the performance of a multilevel multiple imputation (multilevel MI) approach relative to other approaches that do not account for such structures in a Monte Carlo simulation study. Empirical EMA data from a tobacco cessation study are used to demonstrate the utility of the multilevel MI approach, and the implications of separating participant- and study-initiated EMAs in evaluating individuals’ affective dynamics and urge.