학술논문
The mediating effect of mood spectrum on the relationship between autistic traits and catatonia spectrum
Document Type
article
Author
Liliana Dell’Osso; Giulia Amatori; Barbara Carpita; Gabriele Massimetti; Benedetta Nardi; Davide Gravina; Francesca Benedetti; Chiara Bonelli; Danila Casagrande; Mario Luciano; Isabella Berardelli; Natascia Brondino; Marianna De Gregorio; Giacomo Deste; Marta Nola; Antonino Reitano; Maria Rosaria Anna Muscatello; Maurizio Pompili; Pierluigi Politi; Antonio Vita; Mario Maj
Source
Frontiers in Psychiatry, Vol 14 (2023)
Subject
Language
English
ISSN
1664-0640
Abstract
BackgroundIn the recent years, several studies have shown a correlation between autism spectrum disorder (ASD) and catatonia. It is also known that both conditions are found to be associated with mood disorders. This study aimed to investigate the relationship between autistic traits and catatonic symptoms, as well as the potential mediating role of mood disorder spectrum in the relationship between them.MethodsThe total sample of 514 subjects was composed by four diagnostic groups, composed by patients affected by catatonia (CTN), borderline personality disorder (BPD), major depressive disorder (MDD) and healthy controls (HC). Subjects were assessed with the SCID-5-RV, the Adult Autism Subthreshold Spectrum (AdAS Spectrum) and the Catatonia Spectrum (CS) and the Mood Spectrum Self-Report (MOODS-SR). Statistical analyses included Pearson’s coefficient calculation, multiple linear regression, and mediation analysis.Resultsall the correlations appear to be strongly positive and significant with the strongest coefficient emerging between AdAS Spectrum total score and CS total score (r = 0.762, p