학술논문
Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation
Document Type
article
Author
Source
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
MIF is a cytokine best known for its modulatory effect on expression of proinflammatory cytokines. Here the authors show that MIF facilitates the NLRP3–vimentin interaction, resulting in Nlrp3 inflammasome activation.