학술논문
A snapshot of antimicrobial resistance in Mexico. Results from 47 centers from 20 states during a six-month period.
Document Type
article
Author
Elvira Garza-González; Rayo Morfín-Otero; Soraya Mendoza-Olazarán; Paola Bocanegra-Ibarias; Samantha Flores-Treviño; Eduardo Rodríguez-Noriega; Alfredo Ponce-de-León; Domingo Sanchez-Francia; Rafael Franco-Cendejas; Sara Arroyo-Escalante; Consuelo Velázquez-Acosta; Fabián Rojas-Larios; Luis J Quintanilla; Joyarit Y Maldonado-Anicacio; Rafael Martínez-Miranda; Heidy L Ostos-Cantú; Abraham Gomez-Choel; Juan L Jaime-Sanchez; Laura K Avilés-Benítez; José M Feliciano-Guzmán; Cynthia D Peña-López; Carlos A Couoh-May; Aaron Molina-Jaimes; Elda G Vázquez-Narvaez; Joaquín Rincón-Zuno; Raúl Rivera-Garay; Aurelio Galindo-Espinoza; Andrés Martínez-Ramirez; Javier P Mora; Reyna E Corte-Rojas; Ismelda López-Ovilla; Víctor A Monroy-Colin; Juan M Barajas-Magallón; Cecilia T Morales-De-la-Peña; Efrén Aguirre-Burciaga; Mabel Coronado-Ramírez; Alina A Rosales-García; María-de-J Ayala-Tarín; Silvia Sida-Rodríguez; Bertha A Pérez-Vega; América Navarro-Rodríguez; Gloria E Juárez-Velázquez; Carlos Miguel Cetina-Umaña; Juan P Mena-Ramírez; Jorge Canizales-Oviedo; Martha Irene Moreno-Méndez; Daniel Romero-Romero; Alejandra Arévalo-Mejía; Dulce Isabel Cobos-Canul; Gilberto Aguilar-Orozco; Jesús Silva-Sánchez; Adrián Camacho-Ortiz
Source
PLoS ONE, Vol 14, Iss 3, p e0209865 (2019)
Subject
Language
English
ISSN
1932-6203
Abstract
AIM:We aimed to assess the resistance rates of antimicrobial-resistant, in bacterial pathogens of epidemiological importance in 47 Mexican centers. MATERIAL AND METHODS:In this retrospective study, we included a stratified sample of 47 centers, covering 20 Mexican states. Selected isolates considered as potential causatives of disease collected over a 6-month period were included. Laboratories employed their usual methods to perform microbiological studies. The results were deposited into a database and analyzed with the WHONET 5.6 software. RESULTS:In this 6-month study, a total of 22,943 strains were included. Regarding Gram-negatives, carbapenem resistance was detected in ≤ 3% in Escherichia coli, 12.5% in Klebsiella sp. and Enterobacter sp., and up to 40% in Pseudomonas aeruginosa; in the latter, the resistance rate for piperacillin-tazobactam (TZP) was as high as 19.1%. In Acinetobacter sp., resistance rates for cefepime, ciprofloxacin, meropenem, and TZP were higher than 50%. Regarding Gram-positives, methicillin resistance in Staphylococcus aureus (MRSA) was as high as 21.4%, and vancomycin (VAN) resistance reached up to 21% in Enterococcus faecium. Acinetobacter sp. presented the highest multidrug resistance (53%) followed by Klebsiella sp. (22.6%) and E. coli (19.4%). CONCLUSION:The multidrug resistance of Acinetobacter sp., Klebsiella sp. and E. coli and the carbapenem resistance in specific groups of enterobacteria deserve special attention in Mexico. Vancomycin-resistant enterococci (VRE) and MRSA are common in our hospitals. Our results present valuable information for the implementation of measures to control drug resistance.