학술논문
Evaluating the Feasibility of Hydrogel-Based Neural Cell Sprays
Document Type
article
Source
Journal of Functional Biomaterials, Vol 14, Iss 10, p 527 (2023)
Subject
Language
English
ISSN
2079-4983
Abstract
Neurological injuries have poor prognoses with serious clinical sequelae. Stem cell transplantation enhances neural repair but is hampered by low graft survival (ca. 80%) and marker expression/proliferative potential of hydrogel-sprayed astrocytes was retained. Combining a cell spray format with polymer encapsulation technologies could form the basis of a non-invasive graft delivery method, offering potential advantages over current cell delivery approaches.