학술논문
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis
Document Type
article
Author
Steven Bell; Andreas S. Rigas; Magnus K. Magnusson; Egil Ferkingstad; Elias Allara; Gyda Bjornsdottir; Anna Ramond; Erik Sørensen; Gisli H. Halldorsson; Dirk S. Paul; Kristoffer S. Burgdorf; Hannes P. Eggertsson; Joanna M. M. Howson; Lise W. Thørner; Snaedis Kristmundsdottir; William J. Astle; Christian Erikstrup; Jon K. Sigurdsson; Dragana Vuckovic; Khoa M. Dinh; Vinicius Tragante; Praveen Surendran; Ole B. Pedersen; Brynjar Vidarsson; Tao Jiang; Helene M. Paarup; Pall T. Onundarson; Parsa Akbari; Kaspar R. Nielsen; Sigrun H. Lund; Kristinn Juliusson; Magnus I. Magnusson; Michael L. Frigge; Asmundur Oddsson; Isleifur Olafsson; Stephen Kaptoge; Henrik Hjalgrim; Gudmundur Runarsson; Angela M. Wood; Ingileif Jonsdottir; Thomas F. Hansen; Olof Sigurdardottir; Hreinn Stefansson; David Rye; DBDS Genomic Consortium; James E. Peters; David Westergaard; Hilma Holm; Nicole Soranzo; Karina Banasik; Gudmar Thorleifsson; Willem H. Ouwehand; Unnur Thorsteinsdottir; David J. Roberts; Patrick Sulem; Adam S. Butterworth; Daniel F. Gudbjartsson; John Danesh; Søren Brunak; Emanuele Di Angelantonio; Henrik Ullum; Kari Stefansson
Source
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Subject
Language
English
ISSN
2399-3642
Abstract
Bell et al. report 46 new loci associated with biomarkers of iron homeostasis, including ferritin levels, iron binding capacity, and iron saturation, in the Icelandic, Danish and UK populations. The associated loci point to new iron-regulating proteins and important genetic differences between men and women.