학술논문

Brentuximab vedotin in children and adolescents with Hodgkin’s lymphoma and anaplastic large cell lymphoma – literature review and own experience
Document Type
article
Source
Онкогематология, Vol 11, Iss 1, Pp 8-13 (2016)
Subject
hodgkin’s lymphoma
immunohistochemistry
refractory
cd30
brentuximab vedotin
anaplastic large cell lymphoma
Diseases of the blood and blood-forming organs
RC633-647.5
Language
Russian
ISSN
1818-8346
2413-4023
Abstract
Despite significant advances in the treatment of lymphomas in children remain a small proportion of patients with refractory or recurrent disease. An effective approach to the treatment of such patients – not only is the second line chemotherapy, but the use of the new targeted therapies. An example of this approach is the use of brentuximab vedotin (antibody-drug conjugate directed to the CD30) in relapsed Hodgkin’s lymphoma and anaplastic large cell lymphoma. Literature review and own experience of using this drug in children are describes in this article.