학술논문

Non-functional urinary bladder paraganglioma with negative Ga-DOTA-NOC PET/CT uptake
Document Type
article
Source
The Egyptian Journal of Radiology and Nuclear Medicine, Vol 52, Iss 1, Pp 1-6 (2021)
Subject
Paraganglioma
Urinary bladder
Non-functional
Computed tomography
DOTA-NOC PET/CT
Medical physics. Medical radiology. Nuclear medicine
R895-920
Language
English
ISSN
2090-4762
Abstract
Abstract Background Paraganglioma of the urinary bladder is a very rare benign tumor that constitutes less than 0.5% of all bladder tumors. It can be functional and non-functional. Functional tumors present with symptoms of catecholamine excess, and non-functional tumors usually remain asymptomatic. Case presentation Here, we present a case of non-functional urinary bladder paraganglioma in a 36-year-old female who presented to us with a history of intermittent hematuria. The routine hematological and biochemical parameters were within normal limits. Diagnostic computed tomography (CT) revealed a hypervascular lesion in the urinary bladder dome with no significant uptake in gallium-68-labelled-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid peptides-NaI3-octreotide positron emission tomography (DOTA-NOC PET/CT). Histopathology and immunohistochemistry confirmed the diagnosis of paraganglioma. Conclusion We present this case because of the rare location of paraganglioma in the urinary bladder and being non-functional with low/absent somatostatin receptor expression.