학술논문
Use of zinc deposited in deciduous teeth as a retrospective measurement of dietary zinc exposure during early development
Document Type
article
Author
Source
Frontiers in Oral Health, Vol 4 (2023)
Subject
Language
English
ISSN
2673-4842
Abstract
PurposeWe proposed that zinc (Zn) deposition in deciduous teeth would be a timed record of exposure to this essential micronutrient over very early life. We tested this hypothesis by gathering information on the maternal and child's diet during pregnancy and early infancy and measuring mineral deposition in the dentine at points during deciduous tooth development.MethodsWe developed a short food frequency questionnaire (S-FFQ) to record consumption of food containing Zn during pregnancy and over the first year of life of the child in an Indonesian population. Zn, Sr and Ca were measured by laser ablation ICP-MS in a series of points across the developmental timeline in deciduous teeth extracted from 18 children undergoing the process as part of dental treatment whose mothers completed the SFFQ. Mothers and children were classified into either high Zn or low Zn groups according to calculated daily Zn intake.ResultsThe Zn/Sr ratio in dentine deposited over late pregnancy and 0–3 months post-partum was higher (p