학술논문

Prevalence and predictors of chronic kidney disease of undetermined causes (CKDu) in Western Kenya’s 'sugar belt': a cross-sectional study
Document Type
article
Source
BMC Nephrology, Vol 24, Iss 1, Pp 1-14 (2023)
Subject
Chronic kidney disease of undetermined causes
HIV
Occupational health
Environmental epidemiology
Global health
Diseases of the genitourinary system. Urology
RC870-923
Language
English
ISSN
1471-2369
Abstract
Abstract Background Epidemics of chronic kidney disease of undetermined causes (CKDu) among young male agricultural workers have been observed in many tropical regions. Western Kenya has similar climatic and occupational characteristics as many of those areas. The study objectives were to characterize prevalence and predictors of CKDu, such as, HIV, a known cause of CKD, in a sugarcane growing region of Kenya; and to estimate prevalence of CKDu across occupational categories and evaluate if physically demanding work or sugarcane work are associated with reduced eGFR. Methods The Disadvantaged Populations eGFR Epidemiology Study (DEGREE) protocol was followed in a cross-sectional study conducted in Kisumu County, Western Kenya. Multivariate logistic regression was performed to identify predictors of reduced eGFR. Results Among 782 adults the prevalence of eGFR