학술논문
Scalable total synthesis and comprehensive structure–activity relationship studies of the phytotoxin coronatine
Document Type
article
Author
Source
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Subject
Language
English
ISSN
2041-1723
Abstract
Development of comprehensive structure–activity relationships for coronatine has been a major goal in the agrochemical industry. Here, the authors report the gram-scale production and structure–activity relationship of parent coronafacic acid and ultimately rationalise the biological activity of analogues of this phytotoxin.