학술논문

Updates on radiotherapy-immunotherapy combinations: Proceedings of 6th annual ImmunoRad conference
Document Type
article
Source
OncoImmunology, Vol 12, Iss 1 (2023)
Subject
dose and fractionation
FLASH radiotherapy
immune checkpoint inhibitors
immunomodulators
lymph node sparing
tumor-associated macrophages
Immunologic diseases. Allergy
RC581-607
Neoplasms. Tumors. Oncology. Including cancer and carcinogens
RC254-282
Language
English
ISSN
2162402X
2162-402X
Abstract
ABSTRACTFocal radiation therapy (RT) has attracted considerable attention as a combinatorial partner for immunotherapy (IT), largely reflecting a well-defined, predictable safety profile and at least some potential for immunostimulation. However, only a few RT-IT combinations have been tested successfully in patients with cancer, highlighting the urgent need for an improved understanding of the interaction between RT and IT in both preclinical and clinical scenarios. Every year since 2016, ImmunoRad gathers experts working at the interface between RT and IT to provide a forum for education and discussion, with the ultimate goal of fostering progress in the field at both preclinical and clinical levels. Here, we summarize the key concepts and findings presented at the Sixth Annual ImmunoRad conference.