학술논문

Dynamic Biobanking for Advancing Breast Cancer Research
Document Type
article
Source
Journal of Personalized Medicine, Vol 13, Iss 2, p 360 (2023)
Subject
breast cancer
translational research
precision medicine
electronic health records
genomics
health informatics
Medicine
Language
English
ISSN
2075-4426
Abstract
Longitudinal patient biospecimens and data advance breast cancer research through enabling precision medicine approaches for identifying risk, early diagnosis, improved disease management and targeted therapy. Cancer biobanks must evolve to provide not only access to high-quality annotated biospecimens and rich associated data, but also the tools required to harness these data. We present the Breast Cancer Now Tissue Bank centre at the Barts Cancer Institute as an exemplar of a dynamic biobanking ecosystem that hosts and links longitudinal biospecimens and multimodal data including electronic health records, genomic and imaging data, offered alongside integrated data sharing and analytics tools. We demonstrate how such an ecosystem can inform precision medicine efforts in breast cancer research.