학술논문

ShinyGAStool: A user-friendly tool for candidate gene association studies
Document Type
article
Source
SoftwareX, Vol 21, Iss , Pp 101274- (2023)
Subject
Genetic association
Regression analysis
Single nucleotide polymorphism
R shiny
Computer software
QA76.75-76.765
Language
English
ISSN
2352-7110
Abstract
A major barrier to the analysis of genotyping and sequencing data is the relative complexity of the tools needed to perform the analysis. We developed shinyGAStool, an open source tool that enables the user to perform a candidate gene association analysis from large datasets in an easy to use tool from a web browser. With a 3-step workflow, shinyGAStool allows the user to (1) identify and explore distributions of the phenotype and covariates, (2) select genes and variants to evaluate, and (3) run an association analysis linking the two.